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RO6889678
CAS No. : 1578153-27-1
Biological Activity:RO6889678 is a highly potent HBV capsid formation inhibitor with a complex absorption, distribution, metabolism, and excretion (ADME) profile. RO6889678 is a potent inducer of CYP3A4 and coregulated proteins in human hepatocytes. RO6889678 is metabolized by a combination of CYP3A4-mediated oxidation and UDP-glucuronosyltransferase UGT1A3- and UGT1A1-mediated direct glucuronidation.
Research Area:Infection|Metabolic Disease
Targets:HBV|Cytochrome P450
Related Small Molecules:SR9186;AMG-208;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Hypericin;DVR-01;Bicyclol;Galeterone;Catalpol;Ranitidine;Schisantherin C;Bergapten;Ginsenoside Rd;AS1810722;Isoglycycoumarin;Polygalaxanthone III;Phenyltoloxamine;Ezutromid;Seviteronel;HBV-IN-20;β-Apo-8′-carotenal;Diosmetin-d3;EDP-305;Fipronil;Glycosmisic acid
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