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Ro 5212773
CAS No. : 1110781-88-8
Biological Activity:Ro 5212773 (EPPTB) is a potent and selective trace amine-associated receptor 1 (TAAR1) antagonist (Ki=0.9 nM for mouse TAAR1), with no significant effects on other TAARs. TAAR1 is a G protein-coupled receptor (GPCR) that is nonselectively activated by endogenous metabolites of amino acids[2].
Research Area:Neurological Disease
Targets:Trace Amine-associated Receptor (TAAR)
Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Lipid Metabolism Compound Library ;
Related Small Molecules:Ro 5212773-d5;RO5166017;RO5263397;RO5256390;Ralmitaront
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