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R121919
CAS No. : 195055-03-9
Biological Activity：R121919 (NBI30775) is a potent small-molecule CRF1 receptor antagonist with a Ki of 2 to 5 nM for the CRF1 receptor and over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types.
Research Area：Neurological Disease|Endocrinology
Targets：CRFR
Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Endocrinology Compound Library;Targeted Diversity Library;Human Metabolite Library;
Related Small Molecules:Stresscopin-related peptide (human);Sauvagine;CRF(6-33)(human) TFA;NBI-27914;Urocortin III, mouse;Emicerfont;CP 316311;Pexacerfont;Urotensin I TFA;Urocortin, rat TFA;Urocortin II, human TFA;α-Helical CRF(9-41);CP 376395;Urocortin, human;CRF, bovine TFA;Tildacerfont;Cortagine;Antisauvagine-30 TFA
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