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QM31
CAS No. : 937735-00-7
Biological Activity：QM31 (SVT016426), a cytoprotective agent, is a selective inhibitor of Apaf-1. QM31 inhibits the formation of the apoptosome (IC50=7.9μM), the caspase activation complex composed by Apaf-1, cytochrome c, dATP and caspase-9. QM31 exerts mitochondrioprotective functions and interferes with the intra-S-phase DNA damage checkpoint[2].
Research Area：Cancer
Targets：Caspase
Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Anti-Cancer Compound Library;
Related Small Molecules:Dehydrocorydaline;Z-DEVD-AMC;p-nitro-Pifithrin-α;ML132;L67;AKN-028 acetate;Ossirene;δ-Secretase inhibitor 11;Anticancer agent 63;Fenbufen-d9;Penicillic acid;Sesamolin;PI-1840;5,7-Dihydroxychromone;HDAC1-IN-5;Ac-DEVD-pNA;Crustecdysone;Caspase-3-IN-1;PARP-1-IN-2;Z-WEHD-FMK;Mca-YVADAP-Lys(Dnp)-OH;Aspirin;BOC-D-FMK;Ac-LEHD-AFC;Asperosaponin VI;Thevetiaflavone
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