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QL-X-138

CAS No. : 1469988-63-3

Biological Activity：QL-X-138 is a potent and selective BTK/MNK dual kinase inhibitor, exhibits covalent binding to BTK and non-covalent binding to MNK. QL-X-138 shows IC₅₀s of 9.4 nM, 107.4 nM and 26 nM for BTK, MNK1 and MNK2 kinases respectively. QL-X-138 also shows anti-dengue virus 2 activity, with an IC₅₀ of 3.5 μM. QL-X-138 can be used for the research of B-cell malignancies^[2].

Research Area：Cancer|Infection

Targets：MNK|Influenza Virus|Btk

Related Small Molecules:JAK3/BTK-IN-1;Curcumin;(R)-Camptothecin-d5;Glaucine;Elsubrutinib;Hypericin;Neuraminidase-IN-3;ARQ 531;PF-06250112;PCI 29732;FGI-106 tetrahydrochloride;Molnupiravir;Onradivir;SP187;Nuezhenidic acid;Ketotifen fumarate;Baloxavir-d5;Coptisine chloride;Ginsenoside Rb2;T-1105;Tetrahydroepiberberine;CHMFL-EGFR-202;JNJ4796;Avitinib;RN486;Loratadine-d5;GDC-0834 Racemate

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