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PROTAC SGK3 degrader-1
CAS No. : 2381320-35-8
Biological Activity:PROTAC SGK3 degrader-1 (SGK3-PROTAC1), is a potent SKG3 degrader based on von Hippel-Lindau ligand. PROTAC SGK3 degrader-1 (0.3 μM) induces 50% degradation of endogenous SGK3 within 2 hours, with maximal 80% degradation observed within 8 hours, accompanied by a loss of phosphorylation of NDRG1 (an SGK3 substrate).
Research Area:Cancer
Targets:SGK|PROTACs
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:PROTAC Sirt2 Degrader-1;DB0614;PROTAC VEGFR-2 degrader-2;dTAGV-1-NEG;CCT367766 formic;HDAC6 degrader-1;PROTAC Axl Degrader 2;PhosTAC7;MS98;JPS014;PROTAC PARP1 degrader;MD-224;FKBP12 PROTAC dTAG-7;SJ10542;MS8815;RIP2 Kinase Inhibitor 4;PROTAC EGFR degrader 7;PF-4950834;SJ995973;CC-885-CH2-PEG1-NH-CH3;dFKBP-1;MI-389;BSJ-4-116;MS4078;PZ703b;DP-C-4;KB02-JQ1;QCA570;NJH-2-056;dTAG-47
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