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Ponsegromab
CAS No. : 2368950-15-4
Biological Activity:Ponsegromab (PF 06946860) is a potent and selective humanized anti-GDF15 antibody inhibitor with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the binding of GDF15 to GFRAL, thereby blocking GDF15/GFRAL-mediated signaling. Ponsegromab can be used in the research of cancers.
Research Area:Cancer
Targets:TGF-beta/Smad
Related Small Molecules:TGFβ-IN-2;SRI-011381;Isoviolanthin;ALK5-IN-32;Asiaticoside;Halofuginone hydrobromide;ALK5-IN-28;Oxymatrine;Trabedersen;CCT365623 hydrochloride;Butaprost;Disitertide TFA;ALK5-IN-34;Alantolactone;(E)-SIS3;Chebulinic acid;R-268712;Mongersen;EMT inhibitor-1;IDE 2;10,11-Dehydrocurvularin
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