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Ponatinib hydrochloride
CAS No. : 1114544-31-8
Biological Activity：Ponatinib (AP24534) hydrochloride is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.
Research Area：Cancer
Targets：Autophagy|VEGFR|Bcr-Abl|Src|FGFR|PDGFR
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Autophagy Compound Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Alzheimer’s Disease Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Targeted Therapy Drug Library ;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Rare Diseases Drug Library;Anti-Colorectal Cancer Compound Library ;Children’s Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:(Z)-FeCP-oxindole;KB SRC 4;Tirbanibulin dihydrochloride;VEGFR-2-IN-24;BMS-690514;AT9283;Bafetinib;PROTAC VEGFR-2 degrader-2;Pivanex;p60c-src substrate II;Henatinib;SNIPER(ABL)-039;PI3K/VEGFR2-IN-1;Flumatinib mesylate;IHMT-TRK-284;Caffeic acid-pYEEIE TFA;Ferulic acid-13C3;PDGFRα/FLT3-ITD-IN-2;PP2;FGFR-IN-7;PP58;Hydroxytanshinone IIA;Chiauranib;Foretinib;ZM323881 hydrochloride
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