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Pioglitazone
CAS No. : 111025-46-8
Biological Activity:Pioglitazone (U 72107) is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone can be used in diabetes research[2][3][4].
Research Area:Metabolic Disease|Cancer
Targets:Ferroptosis|PPAR
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Anti-diabetic Compound Library;Ferroptosis Compound Library;NMPA-Approved Drug Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Lipid Metabolism Compound Library ;Tumorigenesis-Related Compound Library;Rare Diseases Drug Library;Antidepressant Compound Library;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Nuclear Receptor Compound Library;Non-steroidal Anti-Inflammatory Compound Library;Osteogenesis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:CIL56;DB0614;Ciclopirox-d11;Ciclopirox olamine;Curcumin;Falcarindiol;5-Aminosalicylic Acid-D3 hydrochloride;Retinoic acid;PPARγ agonist 7;Licarin B;(-)-Epicatechin;Mifobate;Eugenol-d3;Artemisinin-d3;MMRi62;Daidzein-d4;Ciglitazone;UAMC-3203;L-Glutamic acid-15N,d5;MK-886;Chalcones A-N-5
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