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Phenindione
CAS No. : 83-12-5
Biological Activity：Phenindione is an anticoagulant which functions as a Vitamin K antagonist.
Target: Others
Phenindione(Rectadione) is an anticoagulant which functions as a Vitamin K antagonist. A lymphocyte transformation test showed proliferation of T-cells from the hypersensitive patient, but not from four controls on exposure to phenindione in vitro. Drug-specific T-cell clones were generated and characterized in terms of their phenotype, functionality, and mechanism of antigen presentation. Forty-three human leukocyte antigen class II restricted CD4+ αβ T-cell clones were identified. T-cell activation resulted in the secretion of interferon-γ and interleukin-5 [1].
Research Area：Cardiovascular Disease
Targets：Others
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