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PF-06380101
CAS No. : 1436391-86-4
Biological Activity：PF-06380101 (Aur0101), an auristatin microtubule inhibitor, is a cytotoxic Dolastatin 10 analogue. PF-06380101 (Aur0101) shows excellent potencies in tumor cell proliferation assays and differential ADME properties when compared to other synthetic auristatin analogues that are used in the preparation of ADCs.
Research Area：Cancer
Targets：Microtubule/Tubulin|ADC Cytotoxin
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Toxins for Antibody-Drug Conjugate Research Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Cytoskeleton Compound Library;Anti-Lung Cancer Compound Library;Protein-protein Interaction Inhibitor Library;
Related Small Molecules:Sandramycin;Tirbanibulin dihydrochloride;Tilavonemab;(R)-Camptothecin-d5;Tau tracer 1;Dolastatin 10;Ceratamine A;INX-SM-56;Batabulin sodium;OXi8007;DC10SMe;Antitumor agent-68;Dictyostatin;Tubulin inhibitor 6;Rebeccamycin;Duocarmycin TM;Oryzalin;Tubulin inhibitor 25;Fmoc-MMAE;Taltobulin;Tubulin inhibitor 16;N-Me-L-Ala-maytansinol;CC-885-CH2-PEG1-NH-CH3;Camptothecin;Epothilone B;TN-16
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