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Perphenazine dihydrochloride
CAS No. : 2015-28-3
Biological Activity:Perphenazine dihydrochloride is an orally active dopamine receptor and histamine-1 receptor antagonist, with Ki values of 0.56 nM (D2), 0.43 nM (D3), 6 nM (5-HT2A), respectively. Perphenazine dihydrochloride also binds to Alpha-1A adrenergic receptor. Perphenazine dihydrochloride inhibits cancer cell proliferation, and induces apoptosis. Perphenazine dihydrochloride can be used in the research of mental disease, cancer, inflammation[3][5].
Research Area:Cancer|Endocrinology|Inflammation/Immunology|Neurological Disease
Targets:Dopamine Receptor|Adrenergic Receptor|5-HT Receptor|Autophagy|Histamine Receptor|Apoptosis
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