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Peldesine
CAS No. : 133432-71-0
Biological Activity:Peldesine (BCX 34) is a potent, competitive, reversible and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50s of 36 nM, 5 nM, and 32 nM for human, rat, and mouse red blood cell (RBC) PNP, respectively. Peldesine is also a T-cell proliferation inhibitor with an IC50 of 800 nM. Peldesine has the potential for cutaneous T-cell lymphoma, psoriasis and HIV infection research[2][3][4].
Research Area:Cancer|Infection|Inflammation/Immunology
Targets:Nucleoside Antimetabolite/Analog|HIV
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