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NS13001
CAS No. : 1063331-94-1
Biological Activity：NS13001 is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels). The EC50s are 1.8 and 0.14 μM for SK2 and SK3, respectively. NS13001 holds promise as a potential therapeutic agent for treatment of spinocerebellar ataxia type 2 (SCA2) and possibly other cerebellar ataxias.
Research Area：Neurological Disease
Targets：Potassium Channel
Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Orally Active Compound Library;Neuroprotective Compound Library;Potassium Channel Compound Library;
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