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NPD-001

CAS No. : 469863-16-9

Biological Activity：NPD-001 is a potent Trypanosoma brucei phosphodiesterases TbrPDEB1 and TbrPDEB2 inhibitor, with IC₅₀ values of 4 and 3 nM, respectively. NPD-001 also inhibits human PDEs (phosphodiesterases). NPD-001 shows good anti trypanosomal activity, with an IC₅₀ of 80 nM.

Research Area：Infection

Targets：Phosphodiesterase (PDE)|Parasite

Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Metabolism/Protease Compound Library;Anti-Alzheimer’s Disease Compound Library;Antiparasitic Compound library;Neurodegenerative Disease-related Compound Library;Anti-Colorectal Cancer Compound Library ;

Related Small Molecules:(+)-Isopulegol;Senazodan hydrochloride;(E/Z)-HA155;Enpp/Carbonic anhydrase-IN-1;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;ATX inhibitor 22;Carbazeran citrate;Bay 60-7550;BC11-38;SQ109;Trypanothione synthetase-IN-3;Deltarasin hydrochloride;Pyrantel;α-Terpinene;Dehydrocorydaline;Glaucine;Ziritaxestat;Niclosamide monohydrate;Febrifugine dihydrochloride;Antimalarial agent 15

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