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NOD1/2 antagonist-1
CAS No. : 2704623-69-6
Biological Activity：NOD1/2 antagonist-1 (compound 36b) is a potent NOD1/2 (nucleotide-binding
oligomerization domain-like receptor 1/2) dual antagonist, with IC50 values of 1.13 (NOD1) and 0.77 μM (NOD2), respectively. NOD1/2 antagonist-1 has a acceptable T1/2 (67.6 min). NOD1/2 antagonist-1 (compound 36b) can improve the antitumor efficacy of Paclitaxel (PTX).
Research Area：Cancer|Inflammation/Immunology
Targets：NOD-like Receptor (NLR)
Related Small Molecules:MCC950;Dapansutrile;NOD-IN-1;NLRP3-IN-4;NLRP3-IN-12;Nigericin;NLRP3-IN-5;β-Aminoarteether;GSK717;NLRP3-IN-NBC6;Selnoflast;BMS-986299;NDT-30805;Licochalcone B;Emlenoflast sodium;AMS-17;NLRP3-IN-6;CY-09;NLRP3/AIM2-IN-1;Muscone;NLRP3-IN-8;INF4E;NLRP3-IN-2
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