NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal)

For research use only. We do not sell to patients.

NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal)

Biological Activity：NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal) (compound 40), a macrocyclic analogue of Ape13, is a potent APJ agonist (Ki=5.7 nM). NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal) exhibits a favorable Gα12-biased signaling and an increased in vivo half-life.

Research Area：Cardiovascular Disease

Targets：Apelin Receptor (APJ)

Related Small Molecules:ML221;Apelin-13 TFA;ML233;[Pyr1]-Apelin-13;APJ receptor agonist 5;APJ receptor agonist 1;ELA-11(human) TFA;AM-8123;Elabela(19-32) TFA;MM 07;APJ receptor agonist 4;ELA-32(human) TFA;Azelaprag;ELA-21 (human);APJ receptor agonist 6;MM 54;CMF019;NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal);Apelin agonist 1;APJ receptor agonist 3

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

About Us:

  • MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
  • Structurally and synthetically diverse biologically active compounds；
  •  roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
  • We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
  • Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；

    • Structurally and synthetically diverse biologically active compounds；

  • Customized order volume ranging from milligrams to kilograms scale；

    • We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.

50K Diversity Library
Top Publications Citing Use of MCE Products
Recombinant Proteins
magnetic-beads