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NH-3

CAS No. : 447415-26-1

Biological Activity：NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC₅₀ of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment^[2]^[3].

Research Area：Neurological Disease

Targets：Thyroid Hormone Receptor

Related Screening Libraries:Bioactive Compound Library Plus;Orally Active Compound Library;Nuclear Receptor Compound Library;Osteogenesis Compound Library;

Related Small Molecules:(D-Trp12,Tyr34)-pTH (7-34) amide (bovine);L-Thyroxine sodium;TR antagonist 1;TRβ agonist 1;1α-Hydroxy-3-epi-vitamin D3;DS08210767;Thyroxine sulfate;Thyroxine hydrochloride-13C6;Parathyroid Hormone (1-34), human, biotinylated;KB130015;Parathyroid hormone (1-34) (rat);Tiratricol;KAT681;Eprotirome;Resmetirom;Glutaurine;PCO371;Parathyroid Hormone (1-34), bovine;Sobetirome;DS69910557;Taltirelin acetate;T3-ATA (S-isomer);Reverse T3

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