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MRS2395
CAS No. : 491611-55-3
Biological Activity：MRS2395, an dipivaloyl derivative, is a potent P2Y12 receptor antagonist. MRS2395 inhibits ADP-induced platelet activation with a Ki of 3.6 μM. MRS2395 inhibits cAMP induced by ADP in rat platelets in the presence of PGE1 with an IC50 of 7 µM. MRS2395 enhances platelet dense granule release in response to TRAP-6[2].
Research Area：Cardiovascular Disease
Targets：P2Y Receptor
Related Small Molecules:YM-254890;BPTU;Uridine 5′-diphosphoglucose disodium salt;AZD1283;Antiplatelet agent 1;NF546;PSB-1114 tetrasodium;Vicagrel;Cangrelor tetrasodium;MRS2179 tetrasodium hydrate;PSB-0739;PIT;MRS2279;MRS2768 tetrasodium salt;PPTN hydrochloride;PSB 0474
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