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Motesanib Diphosphate
CAS No. : 857876-30-3
Biological Activity：Motesanib Diphosphate (AMG 706 Diphosphate) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is approximately 10-fold more selective for VEGFR than PDGFR and Ret.
Research Area：Cancer
Targets：VEGFR|c-Kit
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Human Metabolite Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:(Z)-FeCP-oxindole;VEGFR-2-IN-24;BMS-690514;PROTAC VEGFR-2 degrader-2;Henatinib;PI3K/VEGFR2-IN-1;c-Kit-IN-5-1;Flumatinib mesylate;IHMT-TRK-284;Hydroxytanshinone IIA;Chiauranib;Foretinib;ZM323881 hydrochloride;Pexidartinib;PTC299;ENMD-2076 Tartrate;Aflibercept;SU5408;MAZ51;R1530;AZD2932;R916562
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