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MMV390048
CAS No. : 1314883-11-8
Biological Activity:MMV390048 is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 µM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns. MMV390048 is an antimalarial agent.
Research Area:Infection
Targets:Parasite|PI4K
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Anti-Pancreatic Cancer Compound Library;Antiparasitic Compound library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Glucose Metabolism Compound Library;Cancer Stem Cells Compound Library;
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