ML372

For research use only. We do not sell to patients.

ML372

CAS No. : 1331745-61-9

Biological Activity:ML372 inhibits survival motor neuron (SMN) protein ubiquitination, increases SMN protein stability without affecting mRNA expression. ML372 improves spinal muscular atrophy (SMA) in mice. ML372 is brain penetrant and has a reasonable exposure and half-life in vivo.

Research Area:Neurological Disease

Targets:DNA/RNA Synthesis

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