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MK-8033 hydrochloride
CAS No. : 1283000-43-0
Biological Activity：MK-8033 hydrochloride is an orally active ATP competitive c-Met/Ron dual inhibitor (IC50s: 1 nM (c-Met),7 nM (Ron)), with preferential binding to the activated kinase conformation. MK-8033 hydrochloride can be used in the research of cancers, such as breast and bladder cancers, non-small cell lung cancers (NSCLCs)[2].
Research Area：Cancer
Targets：c-Met/HGFR
Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Orally Active Compound Library;Anti-Lung Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Cancer Stem Cells Compound Library;
Related Small Molecules:AMG-208;D6808;MET kinase-IN-2;c-Met-IN-9;Tyrosine kinase-IN-4;Savolitinib;Foretinib;PF-04217903 phenolsulfonate;MK-2461;XL092;SAR125844;BPI-9016M;Ficlatuzumab;Meleagrin;c-Met inhibitor 1;Pamufetinib;PHA-665752;c-Met/HDAC-IN-2;SU11274;Antitumor agent-45;Capmatinib hydrochloride;SCR-1481B1;SYN1143;Amuvatinib hydrochloride;c-Met/HDAC-IN-3;Gemnelatinib
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