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MK-0159
CAS No. : 2641484-61-7
Biological Activity：MK-0159 (compound 37) is an orally active, potent and selective CD38 inhibitor, with IC50 values of 22, 3, and 70 nM for human, mouse and rat CD38, respectively. MK-0159 also shows good microsomal stability for human and rodent liver microsomes. MK-0159 increases NAD+ (nicotinamide adenine dinucleotide) and reduces ADPR (adenosine diphosphate ribose) in whole blood and heart.
Research Area：Metabolic Disease|Cardiovascular Disease
Targets：CD38
Related Small Molecules:CD38 inhibitor 1;Daratumumab;Ara-F-NAD+;Luteolinidin chloride
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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