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Mizagliflozin
CAS No. : 666843-10-3
Biological Activity：Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic drug that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation.
Research Area：Metabolic Disease
Targets：SGLT
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Anti-diabetic Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;
Related Small Molecules:Luseogliflozin;SGL5213;Tofogliflozin;Trilobatin;TA-1887;SGLT inhibitor-1;Sotagliflozin;Phloretin;Ertugliflozin L-pyroglutamic acid;Ipragliflozin (L-Proline);LX2761;Enavogliflozin;T-1095;HSK0935;Ipragliflozin-d5;Velagliflozin;Kushenol K;Remogliflozin etabonate
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