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Maxacalcitol-d6
Biological Activity：Maxacalcitol-D6 is the deuterated form of Maxacalcitol (22-Oxacalcitriol), which is a non-calcemic vitamin D3 analog and VDR ligand of VDR-like receptors.
IC50 value:
Target:
Maxacalcitol (22-Oxacalcitriol)suppresses parathyroid hormone (PTH) mRNA expression in vitro and in vivo. Maxacalcitol exhibits similar effects to calcitriol in osteoblast-like cells. Maxacalcitol(22-Oxacalcitriol) inhibits tumor growth of osteosarcoma in vitro in combination with all-trans retinoic acid.
Research Area：Metabolic Disease
Targets：VD/VDR
Related Small Molecules:Atocalcitol;VD3-d6;Dihydrotachysterol;Tacalcitol;Impurity F of Calcipotriol;MeTC7;(24R)-MC 976;VDR agonist 1;TEI-9648;CB1151;MC 1046;1alpha, 25-Dihydroxy VD2-13C2;Secalciferol;5,6-trans-Vitamin D3;Chol-5-en-24-al-3β-ol;Vitamin D3-13C3;Vitamin D3-D7;Vitamin D4;Vitamin D2-d6
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