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Lys-CoA TFA
Biological Activity:Lys-CoA TFA is a selective p300 histone acetyltransferase (HAT) inhibitor (IC50=50-500 nM). Lys-CoA TFA displays >100-fold selectivity for p300 over PCAF (IC50=200 μM). Lys-CoA TFA inhibits p300 HAT activity-dependent transcriptional activation[2].
Research Area:Cancer
Targets:Histone Acetyltransferase
Related Small Molecules:Curcumin;GSK4028;CBP/p300-IN-19 hydrochloride;NSC 694621;PCAF-IN-2;I-CBP112;A-485;TPOP146;HAT-IN-1;DS17701585;Histone Acetyltransferase Inhibitor II;NU9056;SYY-B085-1;CF53;CPTH2;Acetaminophen;Naphthol AS-E;Acetaminophen-13C6;NSC 698600;DCH36_06;C646;TTK21;GNE-781;YF-2;CBP/p300-IN-17;GNE-272;PU139
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