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LY 345899
CAS No. : 10538-99-5
Biological Activity：LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inbhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 18 nM for MTHFD1[2][3].
Research Area：Cancer
Targets：Methylenetetrahydrofolate Dehydrogenase (MTHFD)
Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Oxygen Sensing Compound Library;Anti-Cancer Metabolism Compound Library;Targeted Diversity Library;
Related Small Molecules:DS44960156;DS18561882
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