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LEI-106
CAS No. : 1620582-23-1
Biological Activity:LEI-106 is a potent, dual sn-1-Diacylglycerol lipase α (DAGL-α)/ABHD6 inhibitor with an IC50 of 18 nM for DAGL-α and a Ki of 0.8 μM for ABHD6. LEI-106 inhibits the hydrolysis of [14C]-sn-1-oleoyl-2-arachidonoyl-glycerol, the natural substrate of DAGL-α, with a Ki of 0.7 μM.
Research Area:Metabolic Disease
Targets:MAGL
Related Small Molecules:MAGL-IN-6;PF-06795071;JZL195;N-Arachidonyl maleimide;ML-226;JW 642;WWL123;Euphol;ABX-1431;JJKK 048;SAR629;DO-264;FAAH-IN-5;ABD957;JZP-361;MGL-IN-1;JZP-430;KT109;FAAH/MAGL-IN-2;Monoacylglycerol lipase inhibitor 1;KT182;SA57;FAAH/MAGL-IN-1;KML29;ML-211;MJN110;KT185;WWL70;MAGL-IN-5
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