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Leelamine-d4 hydrochloride

Biological Activity：Leelamine-d4 hydrochloride is the deuterium labeled Leelamine hydrochloride. Leelamine hydrochloride is a tricyclic diterpene molecule that is extracted from the bark of pine trees. Leelamine hydrochloride is a cannabinoid receptor type 1 (CB1) agonist and a inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells that is not affected by androgen receptor status. Leelamine hydrochloride suppresses transcriptional activity of androgen receptor, which is known to regulate fatty acid synthesis^[2,3].

Research Area：Cancer|Endocrinology

Targets：Androgen Receptor|Fatty Acid Synthase (FASN)|Cannabinoid Receptor

Related Small Molecules:VPC-14449;Pregnenolone monosulfate sodium;GW842166X;RVD-Hpα TFA;AC-262536;β-Caryophyllene;Hemopressin(rat) TFA;UCM05;GTx-007;AM8936;Pedunculoside;Linuron-d6;Taranabant;MI-136;Lycorine;Bay 59-3074;NESS 0327;CB1-IN-2;Olivetol;CB1/2 agonist 1;Orlistat;N-Oleoyl glycine;CB1 antagonist 1;COR170;VPC-13789;RD162;ARD-2585

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