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Lck Inhibitor
CAS No. : 847950-09-8
Biological Activity：Lck Inhibitor is a potent, orally active Lck (lymphocyte specific kinase) inhibitor with IC50s of 7, 2.1, 4.2 and 200 nM for Lck, Lyn, Src and Syk kinases, respectively. Lck Inhibitor shows >1000-fold selectivity for Lck over MAPK, CDK and RSK family representatives. Lck Inhibitor inhibits T cell proliferation and in vivo models of arthritis.
Research Area：Inflammation/Immunology
Targets：Src
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Reprogramming Compound Library;Orally Active Compound Library;Anti-Pancreatic Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:KB SRC 4;Tirbanibulin dihydrochloride;Bafetinib;p60c-src substrate II;Caffeic acid-pYEEIE TFA;PP2;PP58;ENMD-2076 Tartrate;CH6953755;Fenlean;TL02-59;A-770041;PF 477736;PD166326;Masitinib;Lyn peptide inhibitor TFA;SM1-71;β-Hydroxyisovalerylshikonin;HG-7-85-01;Squarunkin A hydrochloride;1-NM-PP1;MNS;TG 100801;Scutellarein;TG 100572;AMG-47a
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