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LC3-mHTT-IN-AN2
CAS No. : 7758-73-8
Biological Activity：LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
Research Area：Neurological Disease
Targets：Autophagy|ATTECs
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Related Small Molecules:LC3-mHTT-IN-AN1
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