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Lazabemide hydrochloride

CAS No. : 103878-83-7

Biological Activity：Lazabemide hydrochloride (Ro 19-6327 hydrochloride) is a selective, reversible inhibitor of monoamine oxidase B (MAO-B) (IC₅₀=0.03 μM) but less active for MAO-A (IC₅₀>100 μM). Lazabemide  inhibits monoamine uptake at high concentrations, the IC₅₀ values are 86 μM, 123 μM and >500 μM for noradrenalin, serotonin and dopamine uptake, respectively. Lazabemide can be used for the research of parkinson and alzheimer′s disease.

Research Area：Neurological Disease

Targets：Monoamine Oxidase

Related Small Molecules:PXS-4728A;Hypericin;Simtuzumab;SSAO inhibitor-1;5-HT6R/MAO-B modulator 1;Glicoricone;MAO-B-IN-1;LOX-IN-3;LSD1-IN-16;β-Aminopropionitrile;Lazabemide;Monoamine oxidase/Aromatase-IN-1;PXS-5120A;Pirlindole mesylate;SSAO inhibitor-3;Ladostigil hemitartrate;MAO-B-IN-12;Pheniprazine;PF9601N

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