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KAG-308
CAS No. : 1215192-68-9
Biological Activity：KAG-308 is a potent selective and orally active agonist of EP4 receptor (a prostaglandin E2 receptor subtype), suppresses colitis and promotes histological mucosal healing, potently inhibits TNF-α production. KAG-308 shows a Ki and an EC50 of 2.57 nM and 17 nM for human EP4 receptor, respectively, more selective over EP1, EP2, EP3 and IP receptor.
Research Area：Inflammation/Immunology|Endocrinology
Targets：Prostaglandin Receptor
Related Small Molecules:Omidenepag isopropyl;DG-041;8-Isoprostaglandin E2;BAY-6672;trans-Isoferulic acid;GSK-269984A;KMN-80;SC 51089;p-Hydroxycinnamic acid;Pexopiprant;Dinoprost;Sulprostone;Prostaglandin E2;CAY10471 Racemate;Fevipiprant;TG6-10-1;Cicaprost;ER-819762;MRE-269-d6;ONO-8130;KF 13218;Prostaglandin E2-d4
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