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Isoviolanthin
CAS No. : 40788-84-9
Biological Activity:Isoviolanthin, a flavonoid glycoside, could markedly inhibit TGF-β1-mediated migration and invasion by deactivating epithelial-mesenchymal transition (EMT) via the TGF-β/Smad and PI3K/Akt/mTOR pathways in HCC cells. Isoviolanthin exhibits no cytotoxic effects on normal liver LO2 cells.
Research Area:Cancer
Targets:TGF-beta/Smad
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Stem Cell Signaling Compound Library;TGF-beta/Smad Compound Library;Wnt/Hedgehog/Notch Compound Library;Natural Product Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Lipid Compound Library;Medicine Food Homology Compound Library;Phenols Library;Traditional Chinese Medicine Active Compound Library;Flavonoids Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Cancer Natural Product Library;Plant-Sourced Natural Product Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Osteogenesis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:TGFβ-IN-2;SRI-011381;Ponsegromab;ALK5-IN-32;Asiaticoside;Halofuginone hydrobromide;ALK5-IN-28;Oxymatrine;Trabedersen;CCT365623 hydrochloride;Butaprost;Disitertide TFA;ALK5-IN-34;Alantolactone;(E)-SIS3;Chebulinic acid;R-268712;Mongersen;EMT inhibitor-1;IDE 2;10,11-Dehydrocurvularin
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