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Iptacopan

CAS No. : 1644670-37-0

Biological Activity：Iptacopan (LNP023) is a first-in-class, orally bioavailable, highly potent and highly selective factor B inhibitor with an IC₅₀ value of 10 nM. Iptacopan shows direct, reversible, and high-affinity binding to human factor B with a K_D of 7.9 nM. Iptacopan targets the underlying cause of complement 3 glomerulopathy (C3G)^[2].

Research Area：Metabolic Disease|Inflammation/Immunology

Targets：Complement System

Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Chemical Probe Library;Rare Diseases Drug Library;

Related Small Molecules:Cemdisiran;Pelecopan;PMX 205;EG00229;Factor B-IN-2;Tesidolumab;Factor B-IN-3;Avacincaptad pegol;Sutimlimab;FD-IN-1;NDT 9513727;Cyclosporin A;AMY-101;Lipoteichoic acid;Entadamide-A-β-D-glucopyranoside;Compstatin TFA;C5aR-IN-2;BCX 1470;EG01377;TLQP-21;W-54011;Complement C5-IN-1;PMX-53;(Z)-Leukadherin-1

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