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HS-27
CAS No. : 1562024-11-6
Biological Activity:HS-27, a fluorescently-tethered Hsp90 inhibitor, assays surface Hsp90 expression on intact tissue specimens. HS-27 is made up of the core elements of SNX-5422, an Hsp90 inhibitor, tethered via a PEG linker to a fluorescein derivative (fluorescein isothiocyanate or FITC), that binds to ectopically expressed Hsp90. HS-27 has potential use in a see-and-treat paradigm in breast cancer.
Research Area:Cancer
Targets:HSP
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Endoplasmic Reticulum Stress Compound Library;Pyroptosis Compound Library;Cytoskeleton Compound Library;Anti-Breast Cancer Compound Library;Anti-Prostate Cancer Compound Library;
Related Small Molecules:6BrCaQ;116-9e;Paeoniflorin;HDAC/HSP90-IN-4;Debio 0932;MKT-077;Ethoxyquin;Cemdomespib;Apatorsen;HS-131;CH5138303;Pimitespib;NCT-58;MPC-0767;Retaspimycin;BOLD-100;Onalespib;HSP90-IN-12;Palmitic acid-1-13C;Palmitic acid-d3;Feretoside;Palmitic acid-d9;Palmitic acid-13C2;Gamitrinib TPP;JG-98;Gedunin;Rocaglamide;Palmitic acid-13C sodium;AMP-PCP
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