For research use only. We do not sell to patients.
HPK1-IN-3
Biological Activity：HPK1-IN-3 is a potent and selective ATP-competitive hematopoietic progenitor kinase 1 (HPK1; MAP4K1) inhibitor with an IC50 of 0.25 nM. HPK1-IN-3 has IL-2 cellular potency with an EC50 of 108 nM in human peripheral blood mononuclear cells (PBMCs).
Research Area：Inflammation/Immunology
Targets：MAP4K
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Oxygen Sensing Compound Library;Anti-Obesity Compound Library;Targeted Diversity Library;
Related Small Molecules:HPK1-IN-30;HPK1-IN-25;HPK1-IN-18;GNE-495;HPK1-IN-20;KY-05009;HPK1-IN-24;HPK1-IN-10;NCB-0846;HPK1-IN-11;HPK1-IN-9;SS47;HPK1-IN-26;HPK1-IN-7;HPK1-IN-29;HPK1-IN-14;HPK1-IN-28;HPK1-IN-19;TAK1/MAP4K2 inhibitor 1;FLT3/ITD-IN-4;HPK1-IN-17;DB1113;DMX-5804;MAP4K4-IN-3;GNE 220;RET-IN-19;HPK1-IN-27;TL4-12;HPK1-IN-12
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Structurally and synthetically diverse biologically active compounds；
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