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HPGDS inhibitor 1
CAS No. : 1033836-12-2
Biological Activity:HPGDS inhibitor 1 is a potent, selective and orally active Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC50s of 0.6 nM and 32 nM in enzyme and cellular assays, respectively. HPGDS inhibitor 1 does not inhibit human L-PGDS, mPGES, COX-1, COX-2, or 5-LOX.
Research Area:Inflammation/Immunology
Targets:PGE synthase
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Orally Active Compound Library;Targeted Diversity Library;
Related Small Molecules:Bismuth Subsalicylate;PGS-IN-1;Suprofen;Ethyl Caffeate;Limaprost-d3;Sinensetin-d3;Vipoglanstat;Isofezolac;HPGDS inhibitor 2;Sinensetin;Cafestol;BRP-201;Zaloglanstat;CAY10526;Clopirac;mPGES-1-IN-1;hPGDS-IN-1;PF-9184;Pranoprofen;mPGES1-IN-3;YS121;Zomepirac sodium salt;Desoxo-narchinol A;AT-56;Dehydroevodiamine
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