HDAC6/HSP90-IN-1

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HDAC6/HSP90-IN-1

CAS No. : 2411955-43-4

Biological Activity:HDAC6/HSP90-IN-1 (compound 17) is a potent and selective dual inhibitor of HDAC6 and HSP90, with IC50 values of 4.3 and 46.8 nM, respectively. HDAC6/HSP90-IN-1 down-regulates PD-L1 expression in INF-γ treated H1975 lung cancer cells. HDAC6/HSP90-IN-1 inhibits tumor growth in human H1975 xenograft mice.

Research Area:Cancer

Targets:HDAC|HSP

Related Small Molecules:6BrCaQ;Pivanex;116-9e;Crotonoside;MPT0B390;RSC133;HDAC1/6-IN-1;Paeoniflorin;HDAC/HSP90-IN-4;Debio 0932;JPS014;HDAC-IN-4;MKT-077;Ethoxyquin;Cemdomespib;HDAC-IN-27;1-Alaninechlamydocin;SKLB-23bb;Tacedinaline;HPOB;HDAC-IN-28;CG347B;Tubacin;HDAC10-IN-1;Apatorsen;HS-131;CH5138303;HDAC6-IN-6

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