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hCAIX-IN-10
CAS No. : 2497504-72-8
Biological Activity：hCAIX-IN-10 (Compound 6i) is a selective carbonic anhydrase IX and XII inhibitor with Ki s of 61.5 and 586.8 nM for hCA IX and hCA XII, respectively. hCA IX and hCA XII are transmembrane isoforms which have been characterized as biomarkers for several types of tumors. The hCA XII assists in maintenance of acid-base homoeostasis in normal as well as tumor cells.
Research Area：Cancer
Targets：Carbonic Anhydrase
Related Small Molecules:Enpp/Carbonic anhydrase-IN-1;hCAIX-IN-8;Phenylsulfamide;Benzolamide;(E)-Dehydrodiconiferyl alcohol;hCAIX/XII-IN-1;CAXII-IN-1;hCAIX/XII-IN-2;hCAIX-IN-12;Girentuximab;hCAII-IN-2;hCAI/II-IN-1;hCAI/II-IN-4;Dichlorphenamide;hCAIX-IN-16;hCAII-IN-1;Sultiame;hCAII-IN-3;Carbonic anhydrase inhibitor 6;hCAXII-IN-4;U-104;Carbonic anhydrase inhibitor 4;EMAC10101d
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