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Gambogic Acid
CAS No. : 2752-65-0
Biological Activity:Gambogic Acid (Beta-Guttiferrin) is derived from the gamboges resin of the tree Garcinia hanburyi. Gambogic Acid (Beta-Guttiferrin) inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50s of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM.
Research Area:Cancer
Targets:Autophagy|Bcl-2 Family
Related Screening Libraries:Covalent Screening Library Plus;Natural Product Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Natural Product Library;Anti-Cancer Compound Library;Autophagy Compound Library;Covalent Screening Library;Traditional Chinese Medicine Active Compound Library;Anti-Blood Cancer Compound Library;Food-Sourced Compound Library ;Targeted Diversity Library;Anti-Cancer Natural Product Library;Plant-Sourced Natural Product Library;Human Metabolite Library;
Related Small Molecules:BI-3812;Pyridoclax;PUMA BH3 TFA;Dehydrocorydaline;Bufarenogin;Murizatoclax;Obatoclax;CYD-2-11;BM 957;(S)-Gossypol (acetic acid);A-385358;Mcl-1 inhibitor 6;S55746;Anticancer agent 63;MCL-1/BCL-2-IN-2;Anticancer agent 65;(E)-Ferulic acid-d3;Bcl-2-IN-8;S65487 hydrochloride;PI-1840;MIK665;WEHI-539;Bax activator-1;UBX1325;Mcl-1 inhibitor 3;Maritoclax;ABT 737-d8
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