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Galidesivir
CAS No. : 249503-25-1
Biological Activity：Galidesivir (BCX4430), an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 μM[2][3].
Research Area：Infection
Targets：DNA/RNA Synthesis|Filovirus|SARS-CoV
Related Small Molecules:Ametantrone;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;P1788;SARS-CoV-2-IN-33;Thymidine-13C5,15N;NSC 617145;GRL-0496;116-9e;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;6-Thio-2′-Deoxyguanosine;Antitumor agent-74;Grazoprevir potassium salt;Risdiplam;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;TH287 hydrochloride
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