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G140
CAS No. : 2369751-07-3
Biological Activity：G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS), with IC50s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively. G140 has anti-inflammatory activity.
Research Area：Inflammation/Immunology
Targets：Cyclic GMP-AMP Synthase
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;
Related Small Molecules:PF-06928215;G150;RU.521;IRAK4-IN-4
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