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Fostamatinib-d9
CAS No. : 1260832-60-7
Biological Activity：Fostamatinib-d9 (R788-d9) is the deuterium labeled Fostamatinib. Fostamatinib (R788) is the oral prodrug of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM[2]. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM)[3].
Research Area：Inflammation/Immunology|Cancer
Targets：FLT3|Syk
Related Small Molecules:AT9283;(E/Z)-Zotiraciclib;Crotonoside;FLT3-IN-13;PDGFRα/FLT3-ITD-IN-2;FLT3/CDK4-IN-1;Lanraplenib monosuccinate;HP1142;ENMD-2076 Tartrate;ATH686;AZD2932;AKN-028 acetate;FLT3-IN-3;UNC2025 hydrochloride;Tandutinib;OXSI-2;Gilteritinib-d8;PF 477736;(R)-3-Hydroxy Midostaurin;BSc5371;SYK/JAK-IN-1;PRT062607 Hydrochloride;OTS447;MNS;PDGFRα/FLT3-ITD-IN-1;TAK-659 hydrochloride;FLT3-IN-4
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