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Fenofibrate
CAS No. : 49562-28-9
Biological Activity：Fenofibrate is a selective PPARα agonist with an EC50 of 30 μM. Fenofibrate also inhibits human cytochrome P450 isoforms, with IC50s of 0.2, 0.7, 9.7, 4.8 and 142.1 μM for CYP2C19, CYP2B6, CYP2C9, CYP2C8, and CYP3A4, respectively.
Research Area：Cardiovascular Disease|Cancer
Targets：Autophagy|PPAR|Cytochrome P450
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Anti-diabetic Compound Library;Oxygen Sensing Compound Library;Anti-Cardiovascular Disease Compound Library;NMPA-Approved Drug Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Transcription Factor-Targeted Library;Lipid Metabolism Compound Library ;Rare Diseases Drug Library;Children’s Drug Library;Antidepressant Compound Library;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Nuclear Receptor Compound Library;Non-steroidal Anti-Inflammatory Compound Library;Anti-Aging Natural Product Library;
Related Small Molecules:SR9186;AMG-208;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Falcarindiol;Hypericin;5-Aminosalicylic Acid-D3 hydrochloride;Retinoic acid;PPARγ agonist 7;Galeterone;Ranitidine;Licarin B;Bergapten;Mifobate;Ginsenoside Rd;AS1810722;Isoglycycoumarin;Polygalaxanthone III;Phenyltoloxamine;Ezutromid;Seviteronel;β-Apo-8′-carotenal;Diosmetin-d3
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