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FD-IN-1
CAS No. : 1646682-14-5
Biological Activity：FD-IN-1 (Compound 12) is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5 µM, respectively.
Research Area：Inflammation/Immunology
Targets：Complement System
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Orally Active Compound Library;Targeted Diversity Library;
Related Small Molecules:Cemdisiran;Pelecopan;PMX 205;EG00229;Factor B-IN-2;Tesidolumab;Factor B-IN-3;Avacincaptad pegol;Sutimlimab;NDT 9513727;Cyclosporin A;AMY-101;Lipoteichoic acid;Iptacopan;Entadamide-A-β-D-glucopyranoside;Compstatin TFA;C5aR-IN-2;BCX 1470;EG01377;TLQP-21;W-54011;Complement C5-IN-1;PMX-53;(Z)-Leukadherin-1
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