Euphol

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Euphol

CAS No. : 514-47-6

Biological Activity:Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC50=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain.

Research Area:Inflammation/Immunology

Targets:MAGL|Endogenous Metabolite

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