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Esculentoside A
CAS No. : 65497-07-6
Biological Activity:Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta.
Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models[2], has selective inhibitory activity towards cyclooxygenase-2 (COX-2).
Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways[3].
Research Area:Inflammation/Immunology
Targets:NF-κB|COX
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;Natural Product Library;Anti-Aging Compound Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Glycoside Compound Library;Oxygen Sensing Compound Library;Terpenoids Library;Pyroptosis Compound Library;Traditional Chinese Medicine Active Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Food-Sourced Compound Library ;Anti-Liver Cancer Compound Library ;Antidepressant Compound Library;Anti-inflammatory Traditional Chinese Medicine Active Compound Library;Plant-Sourced Natural Product Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Akt/NF-κB/JNK-IN-1;COX-2/5-LOX-IN-3;Icariside F2;IKKγ NBD Inhibitory Peptide TFA;Mangiferin;Antioxidant agent-5;ALPK1-IN-1;Regaloside A;IMD-ferulic;SN52;Ampyrone;COX-2-IN-24;5-Aminosalicylic Acid-D3 hydrochloride;Ginsenoside Rg1;Echinulin;Licochalcone D;Zaltoprofen-d7;QNZ;BIZ 114;NF-κΒ activator 1;Berbamine;α-Vitamin E-d6;1-Hydroxy-ibuprofen;NF-κΒ activator 2;Asaraldehyde;(-)-Epicatechin;20(S)-Ginsenoside Rg3
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