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Equisetin
CAS No. : 57749-43-6
Biological Activity：Equisetin is an N-methylserine-derived acyl tetramic acid isolated from a terrestrial fungus Fusarium equiseti NRRL 5537. Equisetin is a tetramate-containing natural product with antibiotic and cytotoxic activity[2]. Equisetin inhibits the growth of Gram-positive bacteria and HIV-1 integrase activity but shows no activity against Gram-negative bacteria[3]. Equisetin is a Quorum-sensing inhibitor (QSI) that attenuates QS-regulated virulence phenotypes in P. aeruginosa without affecting the growth of bacterias, serves as a leading compound for the treatment of P. aeruginosa infections[4].
Research Area：Infection
Targets：HIV Integrase
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;
Related Small Molecules:XZ426;Integrase-LEDGF/p75 allosteric inhibitor 1;Robinetin;HIV-1 integrase inhibitor 10;Cabotegravir;HIV-1 integrase inhibitor;L-Chicoric Acid;HIV-1 integrase inhibitor 7;HIV-1 integrase inhibitor 8;(S)-BI-1001;Pirmitegravir;Salicylanilide;GSK3739936;(±)-BI-D;Cabotegravir-d5;BMS-707035;Cabotegravir-d3 sodium;MK-2048;Cabotegravir-d3;HIV-1 integrase inhibitor 3;HIV-1 integrase inhibitor 4;Bictegravir sodium
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